BYSTOLIC PI PDF
Learn about prescribing BYSTOLIC® (nebivolol), a beta blocker indicated for the treatment of hypertension. See full Prescribing & Safety Information. BYSTOLIC is a beta-adrenergic blocking agent indicated for . BYSTOLIC is available as tablets for oral administration containing nebivolol hydrochloride. Nebivolol is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in Bystolic is contraindicated in patients with severe bradycardia, heart block with other risks as described in the Adverse Reactions section of its PI.
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BYSTOLIC Formulary Coverage Tool
bystloic From Wikipedia, the free encyclopedia. Several studies have suggested that nebivolol has reduced typical beta-blocker-related side effects, such as fatigueclinical depressionbradycardiaor impotence. Void where prohibited by law, taxed, or restricted. If beta-blocking therapy is withdrawn prior to major surgery, the impaired ability of the heart to respond to reflex adrenergic stimuli may augment the risks of general anesthesia and surgical procedures.
Bystolic therapy is also associated with warnings regarding abrupt cessation of therapy, cardiac failure, angina and acute myocardial infarction, bronchospastic diseases, anesthesia and major surgery, diabetes and hypoglycemia, thyrotoxicosis, peripheral vascular disease, non-dihydropyridine calcium channel blockers use, as well as precautions regarding use with CYP2D6 inhibitors, impaired renal and hepatic function, and anaphylactic reactions.
Beta blockers may mask some of the manifestations of hypoglycemia, particularly tachycardia. Unsourced material may be challenged and removed. Check with your pharmacist for your copay discount. This card expires December 31, Mylan Laboratories licensed the U. When you redeem this card, you certify that you have not submitted and will not submit a claim for reimbursement under any federal, state, or other government programs for this prescription.
Maximum savings limits apply; patient out-of-pocket expense will vary. Check with your pharmacist for your copay discount. Void where prohibited by law, taxed, or restricted. Myocardial infarction and ventricular arrhythmias may occur with or without preceding exacerbation of the angina pectoris. However, such patients may be subject to protracted severe hypotension. Bystolic is associated with a number of serious risks. Views Read Edit View history.
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If you are a patient, and have any questions, please discuss them with your doctor or healthcare provider.
Finally, Bystolic is associated with other risks as described in the Byystolic Reactions section of its PI. This offer is not valid for cash-paying patients. Severe exacerbation of angina, myocardial infarction, and ventricular arrhythmias have been reported following the abrupt discontinuation of therapy with beta blockers. Caution patients without overt coronary artery disease against interruption or abrupt discontinuation of therapy.
Nebivolol | C22H25F2NO4 – PubChem
Patients may not use this offer if they are Medicare-eligible and enrolled in an employer-sponsored bysto,ic plan or prescription drug benefit program bystoljc retirees.
Allergan reserves the right to rescind, revoke, or amend this offer without notice. Concomitant use can increase the risk of bradycardia. The most common side effects people taking BYSTOLIC report are headache, fatigue tirednessdizziness if you feel dizzy, sit or lie down and tell your doctor right awaydiarrhea, nausea, insomnia difficulty falling or staying asleepchest pain, bradycardia slow heartbeatdyspnea shortness of breathrash, and peripheral edema leg swelling due to fluid retention.
J Clin Pharm Ther.
Both digitalis glycosides and beta blockers slow atrioventricular conduction and decrease heart rate. Metabolism of nebivolol is decreased in patients with moderate hepatic impairment. Allergan reserves the right to rescind, revoke, or amend bystplic offer without notice. Patients with a history of severe anaphylactic reactions to a variety of allergens may be more reactive to repeated challenge and may be unresponsive to the usual doses of epinephrine while taking beta blockers.
If BYSTOLIC is to be continued perioperatively, monitor patients closely when anesthetic agents which depress myocardial function, such as ether, cyclopropane, and trichloroethylene are used.
If beta-blocking therapy is withdrawn prior to major surgery, the impaired ability of the heart to respond to reflex adrenergic stimuli may augment the risks of general anesthesia and surgical procedures. When you redeem this card, you certify that you have not submitted and will not submit a claim pj reimbursement under any federal, state, or other government programs for this prescription.
Because of significant negative inotropic and chronotropic effects in patients treated with beta blockers and calcium channel blockers of the verapamil and diltiazem type, monitor the ECG and blood pressure of patients treated concomitantly with these agents.
Advise patients subject to spontaneous hypoglycemia and diabetic patients receiving insulin or oral hypoglycemic agents about these possibilities.
Additionally, difficulty in restarting and maintaining the heartbeat has been reported with beta blockers. Am J Cardiovasc Drugs ; 9 4: Patients may not use this offer if they are Medicare-eligible and enrolled in an employer-sponsored health plan or prescription drug benefit program for retirees. Please see full Prescribing Information.
Renal clearance of nebivolol is decreased in patients with severe renal impairment. Send yourself the Doctor Discussion Guide if you would like to start or continue the conversation about your high blood pressure. Program Terms, Conditions, and Eligibility Criteria: This section does not cite any sources.