ENCEFALITIS LETARGICA PDF
Literalmente, encefalitis significa inflamación del cerebro. En la mayoría de los casos, esta inflamación está provocada por un virus. Se trata de una afección. Doak family. Loomig (A. B.) See Brooks (Amy) Looiuis (A. F.): Paradise cove. Yachts under sail. Lopez Ibor (J.) Encefalitis letargica. Another example might be the “sleeping sickness” (which became known as “ Encefalitis letargica”) which appeared in and quickly spread up in Europe.
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The pathogen issue inevitably remained unresolved, as the etiology of neither influenza nor EL had been clarified by the time the EL epidemic had subsided.
The Berlin physician Werner Gottstein argued in his doctoral thesis published: His two other cases, in contrast, presented encephalitis as a complication of more serious influenza, and were marked by severe, non-localized cerebral manifestations, including deep somnolence and monoplegia. Author information Copyright and License information Disclaimer. During sleep, this center would actively inhibit the cerebral cortex, enncefalitis the level of consciousness.
Encephalitis lethargica epidemica Enceralitis In this respect it has often been observed that the first symptoms of general paralysis of the insane appeared to follow an attack of influenza.
EL might be reported early in its course by an informed physician, but more frequently following the later presentation of post-encephalitic sequelae, or even post mortem on eencefalitis basis of neuropathology.
Were EL-like disorders reported during other influenza epidemics? Epidemic encephalitis encephalitis lethargica John Wright; Bristol: Leichtenstern characterized this encephalitis as:.
Encefalitis (para Padres)
The hepatic aspect of epidemic encephalitis. After repeated questioning, the patient says that it is possible that he had experienced a mild grippe prior to the occurrence of his present complaints Baumann and de Leeuw The New York physician Sachs noted that in many cases, including the majority of those seen in consultation practice, a distinct episode of influenza had preceded the onset of the lettargica disorder by several weeks, similar to post-diphtheritic palsies which also occurred with a delay of weeks after the initial infection.
See other articles in PMC that cite the published article. It is usually temporary but, as your husband experienced, it sometimes is not.
Stern noted that the course of influenza encephalitis was generally rapid, and could resolve itself completely, although focal deficits might persist. Prayers for him and you. Preludes and NocturnesSandman: William Heinemann Medical Books ; London: In the most populous regions on Earth researchers identified only a handful of EL cases, and in neither India nor China did the distribution of letqrgica concord with the course of the influenza pandemic for example: The publisher’s final edited version of this article is available at J Neural Transm.
Further, there was no recognizable correlation between the relative impacts of EL and influenza in particular countries or regions. There was typically a symptom-free interval between the acute and chronic stages of EL, but proposing that a similar interval existed between influenza infection and symptomatic EL is purely speculative. This was perhaps the major reason influenza declined as an explanation for EL towards the end of the s.
There were also areas where the rise and fall of EL and influenza were inversely related, and the case of Portugal where EL preceded influenza Jorge These were more common in the course of influenza encephalitis, often progressing in parallel with other symptoms.
The Prague pathologist Franz Lucksch — reported that was no evidence in Germany for even a single person-to-person transmission of EL Lucksch Government Printing Office; Washington: Treatment for encephalitis lethargica in the early stages is patient stabilization, which may be very difficult. Retrieved 2 May Invasion of brain by neurovirulent influenza A virus after intranasal inoculation.
By the s, the influenza virus had been discovered and was being investigated, as were the arthropod-borne viruses arboviruses responsible necefalitis other encephalitides first described in the letrgica of the EL epidemic. Caduceus Hong Kong ; 5: Influenza was a very public invader, while EL was much stealthier; those who contracted influenza generally returned to full health within months, whereas survival of the acute phase of EL was often the segue to life-long debility.
As early ashowever, there were reports of multiple EL cases where no history of influenza could be established for instance: Studies in famine, disease and society Collected papers on South Asia; no.
Influenza throughout the period in question, however, was more consistent in its ebb and flow across Europe, with the consequence that no correlation between occurrences encefaliyis the two disorders is evident. This sleep therefore appears deceptively similar to normal sleep Economo ap Retrieved 27 December First described by Constantin von Economo. This section does not cite any sources.
Ein Fall von chronischer schubweise verlaufender Encephalitis lethargica. Uses authors parameter All pages needing factual verification Wikipedia articles needing factual verification from December All articles lacking reliable references Articles lacking reliable references from December Articles needing expert attention from December Encefalitsi articles needing expert attention Medicine articles needing expert attention Articles needing additional medical references from December All articles needing additional references Articles requiring reliable medical sources Articles with multiple maintenance issues Infobox medical condition new All articles with unsourced statements Articles with unsourced statements from December Wikipedia articles in need of updating from December All Wikipedia articles in need of updating Articles needing additional references from December Pages with login required references or sources.
There is some evidence, however, that the liver was implicated in EL example: Registration only takes a few minutes to complete.
Encephalitis lethargica – Wikipedia
J Nerv Letargifa Dis. Silent carriers may have played a role in its dissemination, as in poliomyelitis, but would still not entirely overcome the epidemiological difficulties which encumbered the unitarian position see, for example, Levaditi ; Stieflerpp — Leyden E, Guttmann S.
Diplococcus has been implicated as a cause of EL. National Center for Biotechnology Information letsrgica, U. The third and final wave of the influenza pandemic receded from Europe in earlybefore EL had achieved its peak in most countries.
The best described occurrence of somnolence associated with influenza was lanona. But as Hallp noted: Ricerche sulla etiologia della encefalite epidemica con speciale riguardo a sncefalitis particolare virus filtrabile micrococciforme e alla sua recettivita per le scimmie macachi Arch Sci Med Torino ; Two distinct but related questions are being addressed in these papers:.